FEMALE HORMONAL PROFILE / OVULATORY PROFILE (FSH, LH, E2 & PROLACTIN)

You will provide

Blood Sample

This test is for only

Female

Test Preparation

Blood sample should be collected 4 hours after waking

FSH (FOLLICLE-STIMULATING HORMONE)

FSH (follicle-stimulating hormone) is a hormone produced via the pituitary gland in the brain. In women, FSH helps stimulate thegrowth anddevelopmentof ovarian follicles (unfertilised eggs) at some point of the follicularphase of the menstrual cycle. At the time of the menopause, the ovariesquit functioning and FSH levels rise. During pregnancy, oestrogenrangesare high and this makes FSH undetectable.
 

LUTEINIZING HORMONE (LH)

Women's menstrual cycles are divided into 2 phases, the follicular and luteal, by way of a mid-cycle surge of follicle-stimulating hormone (FSH) and LH. The excessive stage of LH (and FSH) at mid-cycle triggers ovulation. LH additionally stimulates the ovaries to produce steroids, primarily estradiol. Estradiol and other steroids help the pituitary to adjust the production of LH. At the time of menopause, the ovaries give up functioning and LH ranges rise. It is recommended to have each LH and FSH examined at the same time.

When do you order FSH and LH lab tests?
In ladies and men, FSH and LH are ordered as phase of the workup of infertility and pituitary or gonadal disorders. FSH may also be ordered to determine if a lady has reached menopause.

Why I Need LH Blood Test?
To measure or reveal your hormone ranges if you are a woman who has unexplained extraordinary menstrual cycles, irregular or heavy vaginal bleeding, infertility, signs of menopause or any other hormonal alterations; fatigue, and moodiness. If you are not experiencing any signs and symptoms it is quiet prudent to analyze what your baseline is, or what is everyday for you, for future health and wellness.

Reference ranges

Normal ranges in women

For females, the ordinary range relies upon on the place they are in their menstrual cycle, as follows:
• follicular phase, or the establishing of the cycle: 1.68–15 IU/L
• mid-cycle peak, round the center of the cycle: 21.9–56.6 IU/L
• luteal phase, which is the end of the cycle: 0.61–16.3 IU/L

For ladies who have gone through menopause, the normal range is 14.2–52.3 IU/L.
If LH degrees are greater than regular when a individual is not ovulating, they may be experiencing menopause. High LH stages may also indicate a pituitary sickness or polycystic ovary syndrome.
If the LH tiers are decrease than normal, it may also indicate:
• malnutrition
• anorexia
• stress
• a pituitary disorder

Normal degrees in children
For girls who are but to go via puberty (aged around 1–10 years), the ordinary range is 0.03–3.9 IU/L.

ESTRADIOL (E2)

Why are these hormone ranges important? Estrogen is a team of three hormones in a woman's body. As the primary part of estrogen produced in the ovaries, Estradiol (or E2) helps facilitate desirable ovulation, conception and pregnancy. It also helps adjust cholesterol degrees and promote bone health in women.

Who need to be tested?

if you are a lady struggling with infertility, or if you are experiencing changes that recommend the onset of menopause. In addition, strongly if you are experiencing any of the following:
• abnormal menstrual cycles
• abnormal or heavy vaginal bleeding
• fatigue
• moodiness
• low intercourse drive
• loss of muscle tone or extended physique fat

Women receiving fertility treatments may also have this test on quite a few times to gauge the degree of estradiol in the ovaries.

Reference Ranges
Depending on the technique of evaluation, reference intervals can fluctuate from one medical lab to another. In addition, the reference vary of estradiol (E2) varies across age and sex.

The conversion element is given below.

Estradiol Hormone: pg/mL x 3.676 = pmol/L (molecular weight = 272)

Reference ranges for serum estradiol
Child <10 years old: < 15 pg/mL
Adult male: 10-50 pg/mL 
Adult Woman:
• Follicular phase: 20-350 pg/mL
• Midcycle peak: 150-750 pg/mL
• Luteal phase: 30-450 pg/mL
• Postmenopause: ≤ 20 pg/mL
Reference levels for urine estradiol (mcg/24 hours)
Child < 10 years old: 0-6

PROLACTIN

Who need to be tested?
Prolactin degrees have to be examined when a pituitary gland tumor (called prolactinoma) is suspected in men or ladies or as a follow-up  to analyze the progress following therapy of prolactinoma.

In women. a prolactin levels in blood is a measure to indicated if she is experiencing infertility or irregular menses or galactorrhea. Galactorrhea is the spontaneous gush of milk from the breast, unassociated with childbirth or nursing. This situation occurs in both girls and men, newborn toddlers and youngsters of each sexes.

Reference Ranges
Your medical doctor will assess whether your ranges are normal based on many factors, such as your overall health.

Women who are  not pregnant < 25 ng/mL
Women who are pregnant 34 to 386 ng/mL
Males < 15 ng/mL

FREQUENTLY ASKED QUESTIONS (FAQs)

Q: What is a female hormonal profile?

A: A female hormonal profile is a series of tests that analyze hormone levels in a woman's body. It provides insights into various hormones such as estrogen, progesterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and others, helping to evaluate reproductive health and detect hormonal imbalances.

Q: Why would someone need a female hormonal profile?

A: A female hormonal profile may be recommended for several reasons. It helps diagnose conditions such as polycystic ovary syndrome (PCOS), infertility, irregular menstrual cycles, menopausal symptoms, and hormonal imbalances. It can also be useful for monitoring hormone replacement therapy or assessing overall reproductive health.

Q: How is a female hormonal profile conducted?

A: A female hormonal profile typically involves a blood test that measures hormone levels during specific phases of the menstrual cycle. The timing and number of tests can vary depending on the purpose of the assessment. Your healthcare provider will provide instructions on when and how to get the tests done.

Q: Are there any preparations required for a female hormonal profile?

A: Yes, certain preparations may be necessary. Your healthcare provider will guide you on specific instructions, which may include fasting for a specific period before the blood test, avoiding certain medications or supplements, and scheduling the test at a specific point in your menstrual cycle.

Q: What can a female hormonal profile reveal?

A: A female hormonal profile can reveal valuable information about hormone levels and potential imbalances. It can help identify issues such as irregular ovulation, hormonal deficiencies, excess androgens, thyroid dysfunction, or other conditions impacting reproductive health.

Q: How do I interpret the results of a female hormonal profile?

A: Interpreting the results of a female hormonal profile is best done in consultation with a healthcare professional. They will assess your results in the context of your symptoms, medical history, and individual circumstances to provide a comprehensive understanding of your hormonal health and recommend appropriate treatment or further investigations if needed.

Q: Can a female hormonal profile help with fertility issues?

A: Yes, a female hormonal profile can be beneficial for assessing fertility issues. By evaluating hormone levels and identifying any irregularities, it can assist in determining potential causes of infertility, guiding appropriate treatment options, and increasing the chances of successful conception.

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