HEPATITIS B VIRUS - VIRAL LOAD
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This test is for both
No specified preparation needed
What is Hepatitis B Virus - Viral Load (HBV)?
The Hepatitis B Virus - Viral Load test is recommended in case of signs and symptoms of acute hepatitis such as loss of appetite, jaundice, nausea, vomiting, and stomach pain.
Why is Hepatitis B Virus - Viral Load performed?
The Hepatitis B Virus - Viral Load, test is performed:
For the management of patients with persistent or chronic hepatitis B infection and presently on antiviral treatment
For the diagnosis of hepatitis B for baseline values and in the course of treatment observes patients response.
What does Hepatitis B Virus - Viral Load Measure?
The Hepatitis B Virus - Viral Load test measures the definite quantity of hepatitis B existing in a blood sample. This test assists ascertains if Hepatitis B Virus (HBV) is getting reproduced in the liver. If HBV viral load is higher than 20,000 international unit per milliliter (IU/mL) in an individualwith detectable Hepatitis B envelope antigen (HBeAg) then it shows that the virus is lively and has the best possible cause of harm to the liver. Similarly, if HBV viral load is higher than 2,000 IU/mL in HBeAg-negative persistent or chronic hepatitis B patients then it shows that the virus is lively and has the best possible cause of harm to the liver. If the HBV viral load is above these numbers, treatment is considered paramount.
INTERPRETING HBV QUANT. RESULTS
|RESULT (in IU/mL)||REMARKS|
Sample furnished does now not contain HBV DNA
HBV DNA detected, but below the decrease limit of linear vary of the assay. These consequences must be interpreted with caution
|>=20 to < 1.7 x 108||HBV DNA detected inside the linear vary of the assay|
|>=1.7 x 108||HBV DNA detected above the linear vary of the assay|
Linear reporting range of the assay is 20 - 1.7 x 108 IU/mL
Conversion factor: 1 IU/mL = 5.82 copies / mL
Results are labeled into three levels
Low or undetectableviral load implies that the lab equipment cannot identify it and viral load is below approximately 300 copies/mL
Moderate ranges are about 10,000 – 90,000 copies/mL
High ranges show amount over 100,000 copies/mL, which is regarded clinically significant
FREQUENTLY ASKED QUESTIONS (FAQs)
Q. How can Hepatitis B virus be transmitted?
Hepatitis B Virus - Viral Load (HBV) is a member of the Hepadnavirus family. It is transmitted notably by body fluids, particularly serum. It can as well be transmitted through sexual transmission or from mother to baby. Majority of the infected individuals recover completely. Whereas, around 1-2% have continual viral replication leading to persistent or chronic hepatitis. The frequency of creating a continual HBV infection in immunocompromised patients is round 5-10% while in neonates it reaches 80%.
Q. Why is it essential to measure Hepatitis B Virus - Viral Load at the point of the cure of HBV infection?
HBV DNA is measured to test if the drug is working to decrease the body’s viral load. Antiviral medicines work by altering the DNA of the virus so that it cannot reproduce effectively. Doctors measure the viral load to be sure that the antiviral is working.
Q. Why is measuring viral load necessary in case of pregnancy?
The pregnant ladies are examined for hepatitis B, along with the measurement of viral load. Pregnant ladies with high viral loads—beyond 200,000 IU/mL—are advised to take antiviral treatment for the duration of their 1/3 trimester of being pregnant according to medical guidelines. This is performed to limit the chance of infecting their newborns. Babies born to HBV-infected ladies can also be infected even if they are immunized at delivery and treated with with HBIG (hepatitis B antibodies) if their mothers have excessive viral loads.
Q. How is the blood sample taken?
The healthcare issuer takes a blood sample from the arm. The place from where the blood is to be withdrawn is cleaned with a swab of rubbing alcohol. This is then accompanied by inserting a small needle which has a tube joined to it for gathering blood. Once the enough blood for gatheredis withdrawn, the needle is removed. The place is then covered with a gauze pad.
Q. Is there any risk related with the withdrawal of blood sample procedure?
As such there is no risk or danger but, in few cases, bruising, bleeding, and infection at the pierce point can be seen. In very few cases, there can be swelling of the vein after the blood is collected.
The information provided herein is for patient general knowledge only and should not be used during any medical emergency, for the diagnosis or treatment of any medical condition. Duplication for personal and commercial use must be authorized in writing by Surjen.com.
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