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Kidneys play a critical role inside the body for elimination of waste products and preservation of water and electrolyte balance. Kidney Function Test (KFT) consists of a group of blood examinations to determine how well the kidneys are working.
Why is Kidney Function Test (KFT) done?
The Kidney Function Test is achieved:
· As part of ordinary fitness checkups
· To help diagnose any sickness affecting the kidneys
· To screen patients at chance for the improvement of any kidney diseases
· To monitor efficacy of kidney disease treatments
What does Kidney Function Test (KFT) Measure?
The kidneys are a couple of bean-shaped organs located on either side of the spinal column within the abdomen toward the back. The kidneys perform a number of vital functions. The most important of those is to filter the blood and separate the waste products generated out of everyday metabolic activities of the person, mainly urea. After the separation, your kidneys excrete these waste products out of the body through urine.
They help in retaining the normal pH levels and water balance of the body. The kidneys also play important roles in the synthesis of Vitamin D and Red Blood Cells (RBCs).
The Kidney Function Test consists of the following tests to reveal kidney function:
Blood Urea Nitrogen (BUN)/ Urea:
Blood Urea Nitrogen is a test to check the amount of urea nitrogen present in the blood. Urea is a nitrogenous byproduct of the metabolism of protein, and its levels in blood serves as an signal of the amount of nitrogen found in blood as urea. In simpler terms, BUN is the degree of the quantity of nitrogen present in blood in the form of urea. High BUN degrees within the blood may be induced as a result of kidney diseases, dehydration and obstruction inside the urinary tract due to kidney stones, prostate gland enlargement, etc.
Urea test measures the level of urea inside the blood. Thefinal waste product formed from the breakdown of proteinsis Urea. Urea is filtered out of the blood with the aid of the kidneys to excrete excess nitrogen present within the blood via urine. Excess of urea in blood is referred to as uremia and may be caused by a number of situations together with kidney diseases.
This test looks at the measures of uric acid inside the blood. Uric acid is a waste product formed from the breakdown of purines, which are important constructing blocks of DNA. It is also produced through the metabolism of proteinaceous food, especially red meat. Uric acid is excreted from the body by using the kidneys through urine and a small portion through stool. The uric acid check indicates the extent of uric acid within the blood and serves as an indirect estimation of the right functioning of the kidneys. The presence of excess amounts of uric acid within the blood is known as hyperuricemia, and causes gout due to the buildup of uric acid crystals in the synovial fluid between joints.
Hyperuricemia additionally causes the formation of difficult lumps of uric acid crystals referred to as tophi underneath the pores and skin and at the pinnacle of the ears. Uric acid crystals can also accumulate inside the kidneys and cause kidney stones.
This test measures the level of Creatinine in blood. Creatinine is a waste product formed from the ordinary breakdown of muscles in the body. Creatinine is almost absolutely excreted with the aid of the kidneys, so their ranges in the blood function is an indication of kidney function. Excess creatinine in the blood may be found because of decreased elimination from the kidneys as well as due to increased creatinine production with the aid of muscular breakdown, ingesting cooked meat, protein supplements, etc.
BUN/Creatinine Ratio compares the stages of nitrogen as urea in blood to the ranges of creatinine in the blood. This ratio actually serves as a fairly accurate representation of kidney function. It is likewise used to check for dehydration for the reason that BUN stage will increase in dehydration while creatinine tiers remain the same. Low BUN to creatinine ratio can be triggered due to a low protein diet, liver cirrhosis, rhabdomyolysis (muscle disease), syndrome of inappropriate antidiuretic hormone secretion (SIADH) as well as throughout pregnancy.
BUN (Blood Unrea Nitrogen):
7 to 20 mg/dL
Adult Female: 2.4 to 6.0 mg/dL
Adult Male: 3.4 to 7.0 mg/dL
Children: 3 to 4 mg/dL
Adult males: 0.6 to 1.2 mg/dL
Adult females: 0.5 to 1.1 mg/dL
12:1 to 20:1
Increased stages of these parameters can indicate a number of conditions and no longer necessarily health disorders. For example, increased creatinine ranges can occur due to heavy exercise, intake of cooked meat, or taking protein supplements aside from kidney diseases. Thus, these parameters also are considered during the interpretation of the exams. Further assessments are carried out to confirm any fitness disorders.
Tests Included (3)
• Uric Acid
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